CONTOUR 20 mg uses and reviw

 

CONTOUR

(Esomeprazole)                          Capsules: 20mg & 40mg

                                                      Lyophilized Inj. 40mg I.V

 

The First in PPI drug class Omeprazole consists of a racemic compound of witch only the S-enantiomer is active, whereas the R enantiomer is not. (CONTOUR) Esomeprazole contain only the purified S-enantiomer (Single Enantiomer).

 

SINGLE ENANTIOMER WITH MORE THERAPEUTIC BENEFITS          

 

Higher healing rates in GERD then other PPIs

 

(CONTOUR) Esomeprazole 40mg tended to have higher endoscopic healing rates than other PPIs GERD patient with Reflux Esophagitis.

 

Endoscopic Healing Rates of Esomeprazole (CONTOUR) were higher at 8th­ week as compared to pantoprazole, Lansoprazole & Omeprazole.

 

95.4%

CONTOUR (Esomeprazole)

91.1%

pantoprazole

89.6%

Lansoprazole

87.7%

Omeprazole

 

  CONTOUR OFFERS

·         Optimum desirable intragastric pH > 4 maintained for Longer duration than other PPIs 

·         Faster relief of Heartburn symptoms than pantoprazole, Lansoprazole & Omeprazole.

·         Higher healing rates in GERD patient with reflux esophagitis than pantoprazole, Lansoprazole & Omeprazole at 8th­ week

·         Available in most affordable Price.

 

Dosage and administrations

ü  Contour 40mg Capsules: Once a day 30 minutes before breakfast.

ü  Contour 40mg I.V: The recommended adult dose is 20mg to 40mg Contour given OD by intravenous injection (not less than 3 minutes) or intravenous infusion (10 to 30 minutes).

In Patient with Risk of Rebreeding of Gastric or Duodenal Ulcer following Therapeutic Endoscopy:

o   Adult dose is 80 mg administered as an intravenous infusion of contour over 30 minutes followed by a continuous infusion of 8mg/h for total treatment duration of 72 hours, that includes initial 30-minutes dose plus 71.5 of continues infusion.    

 

 

CONTOUR-20mg-uses-and-reviw

 


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